Unconstrained by Nature
Beyond What Nature Created
Viruses have naturally evolved to infect cells and, in so doing, deliver their genetic contents into cells. Investigators in the field have engineered viruses for safety (removing their disease-causing capacity) and to use as shuttles for delivering genetic medicines (such genetic medicine delivery tools are called “vectors”). However, nature did not intend for viruses to be therapeutic vectors. For the past decade, 4DMT has been pioneering and industrializing the development of customized and improved viral vectors by using Nobel Prize-winning Directed Evolution technologies. Directed Evolution is a high-throughput platform approach that allows scientists to harness the power of natural selection and invent designer biologics with new and desirable characteristics. At 4DMT, we apply directed evolution principles to create our proprietary vector invention platform we refer to as Therapeutic Vector Evolution.